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Description

We seek highly motivated Postdocs to join the O’Doherty lab.

Our lab studies HIV persistence and what drives the HIV reservoir to contract and expand. In other words, why do some HIV infected cells die while others divide? We probe mechanisms that underlie this phenomenon by studying changes in HIV proviral sequences over time in T cells and their subsets. We then perform in vitro experiments to test our hypotheses using a barcoded virus that enables us to track the fate of individual proviruses in greater depth.

While prior work suggests that the majority of the reservoir resides in the antigen experienced memory CD4+ T cells our work suggests that the antigen inexperienced naive T cells are the real reservoir in disguise. Our findings suggest despite the small size of the naïve reservoir, it has an outsized impact on HIV persistence due to its inherent properties that make it an ideal reservoir.

We recently became interested in the drivers of increased hematopoiesis that is observed in Sickle Cell Disease. We aim to probe the role of inflammation and anemia on hematopoiesis in these individuals using an ex vivo culture systems. We can use this model to study the effect of different modulators on inflammation. Ultimately, we hope this will improve care for individuals with Sickle Cell Disease.

We offer a stimulating environment and are open to new ideas to explain phenomena related to these projects.

Positions are temporary appointments as a research trainee. The initial appointment is for one year, renewal expected if progress is satisfactory and funds are available. Appointments cannot exceed five years.

MINIMUM QUALIFICATIONS: A doctoral degree or equivalent (Ph.D., M.D., ScD., D.V.M., DDS etc) in an appropriate field. Excellent scientific writing ability and strong oral communication skills. The ability to work effectively and collegially with colleagues. Additional qualifications as specified by the Principal Investigator.

PREFERRED QUALIFICATIONS:

Ph.D. in virology, molecular biology, OR bioinformatics.

Applications should include 1) a cover letter that describes why they want to join our team and the research questions they are interested in studying 2) a CV or Resume, and 3) a list of three references with complete contact information

Emory Supports a Diverse and Inclusive Culture

Emory University is dedicated to providing equal opportunities and equal access to all individuals regardless of race, color, religion, ethnic or national origin, gender, genetic information, age, disability, sexual orientation, gender identity, gender expression, and veteran's status. Emory University does not discriminate in admissions, educational programs, or employment on the basis of any factor stated above or prohibited under applicable law. Students, faculty, and staff are assured of participation in University programs and in the use of facilities without such discrimination. Emory University complies with Executive Order 11246, as amended, Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veteran's Readjustment Assistance Act, and applicable executive orders, federal and state regulations regarding nondiscrimination, equal opportunity and affirmative action. Emory University is committed to achieving a diverse workforce through application of its affirmative action, equal opportunity and nondiscrimination policy in all aspects of employment including recruitment, hiring, promotions, transfers, discipline, terminations, wage and salary administration, benefits, and training. Inquiries regarding this policy should be directed to the Emory University Department of Equity and Inclusion, 201 Dowman Drive, Administration Building, Atlanta, GA 30322.

Emory University is committed to providing reasonable accommodations to qualified individuals with disabilities upon request. To request this document in an alternate format or to request a reasonable accommodation, please contact the Department of Accessibility Services at 404-727-9877 (V) | 404-712-2049 (TDD). Please note that one week advance notice is preferred.

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Job Number 123105

Job Type Regular Full-Time

Division School Of Medicine

Department SOM: Pathology: Admin

Campus Location (For Posting) : Location US-GA-Atlanta

Location : Name Bldg 1525 Clifton Road

Required Documents Cover letter, Letter of Interest, List of References

Remote Work Classification Primarily On Campus

Health and Safety Information Working in a laboratory