Job Description

Overview:

Position Title : Analyst I

Business Title : Chemist – RNA Synthesis

Department : ATL

Location : Indianapolis, IN

Reports to : Manager

FLSA : Non-Exempt

Hours Worked : Monday through Friday, forty hours per week.

However, must be flexible to meet the needs of the department and complete other projects as assigned.

Position Summary:

The Chemist is responsible for the synthesis and downstream processing of oligo synthesis using various analytical techniques. AKTA, LC-MS, UPLC, LTQ, QDA analytical instruments are used.

Duties and Responsibilities:

• Downstream processing of synthetic compounds (purification and buffer exchange)

• Carefully prepare laboratory samples from stock/inventory for biological testing

• Maintain accurate and careful records

• Organize inventory of samples

• Synthesis of oligonucleotides on AKTA oligo pilot for solid-phase oligonucleotide synthesis

• Downstream processing of processing of synthetic compounds (purification and buffer exchange)

• Carefully prepare laboratory samples from stock/inventory for biological testing

• Use of general laboratory equipment including but not limited to pipettors, centrifuges, incubators, biological safety cabinets and balances

• Instrumentation for methods and techniques described may include AKTA, LC-MS, UPLC, LTQ, QDA, Nanodrop, etc.

• Data analysis and troubleshooting

• Lab experience with solution preparation, separation, quantification, synthesis methodologies for DNA/RNA, proteins, oligonucleotides, etc.

• Software includes instrument-specific for capturing and analyzing data, Microsoft Office (Word, Excel, PowerPoint, Outlook, Teams/Sharepoint, etc), LIMS, electronic laboratory notebooks, etc.

• Detailed record keeping of daily experiments in ELNs

• General Lab Maintenance

• Follow the guidelines set forth with clients and Company Quality, Health, Safety, Security and Environmental policies and procedures.

• Comply with clients’ and Company management systems in accordance with appropriate regulatory agencies.

• Perform other essential tasks projects and responsibilities as required.

• Other duties as defined by Manager, department needs and workload

Skills & Proficiencies:

• Demonstrated productivity in chemical or biological laboratory setting

• Experience reading and understanding scientific data

• Familiarity with scientific instruments and laboratory techniques

• Experience with RNA handling or isolation

• Experience with nucleotide, nucleoside or oligonucleotide synthesis

• Familiar with dilution and concentration calculations

• Strong organizational skills

• Strong written and oral communication skills

• Confident, execution-focused, and team oriented with a desire to thrive in a fast-paced growing environment

• Written and verbal communication skills including the ability to communicate effectively in a group setting, with colleagues and clients

• Ability to perform multiple tasks

• Ability to organize and prioritize workload to meet or exceed deadlines

• Individual and Team work ethic

• Proficiency with Windows, Word & Excel

• Attention to detail

• Positive attitude, self-motivated, high level of engagement

• Adheres to company values

Education and Experience:

• Degree requirement: Bachelor's Degree in Chemistry, Biochemistry, or closely related field

• Minimum of one (1) year of experience in a chemistry/biology lab setting

An equivalent combination of education and experience may be accepted in lieu of above.