Apply for Job Job ID346544 LocationTwin Cities Job FamilyAcademic Full/Part TimeFull-Time Regular/TemporaryRegular Job Code9546 Employee ClassAcad Prof and Admin Add to Favorite Jobs Email this Job About the Job 75% Characterization of the Clostridioides difficile transferase. The postdoctoral associate will be expected to independently design and carry out experiments aimed at understanding the mechanisms that govern toxin function. 15% Presentation of Data. It is expected that the postdoctoral associate will regularly communicate the results of their work during group-meetings and at scientific conferences. The postdoctoral associate will also be expected to regularly prepare manuscripts and publish their results in top-tier journals. 10% Training of Lab Personnel. The postdoctoral associate will be expected to contribute to the training of junior personnel in the lab. About the Lab: Research in the Sheedlo lab is focused on defining the mechanisms that govern interactions at the host-pathogen interface. Specifically, we are interested in using structural biology (cryo-electron microscopy and X-ray crystallography) to obtain a framework that we can then probe in a physiologically relevant context. Of particular interest is understanding how the Gram-positive pathogen, Clostridioides difficile, uses toxins and effectors to elicit disease. For more information, please visit: Michael Sheedlo, PhD | Medical School - University of Minnesota (umn.edu) Qualifications Required Qualifications: The successful candidate will have recently obtained a PhD in Biology, Biochemistry, Chemistry, Microbiology, Molecular Biology, Structural Biology, or a related field. Previous experience in recombinant protein expression, purification, and characterization is required. Preferred Qualifications: The preferred candidate will have 2-5 years of experience in at least one of the following areas: biochemical assay development, biophysical characterization, and/or high-resolution imaging. Previous experience in determining protein structures using either Cryo-EM or X-ray crystallography is desired, but not mandatory. About the Department Pharmacology is the study of drugs and the mechanisms underlying their beneficial and undesirable effects. Research in pharmacology generates new knowledge and tools that can lead to better treatments for devastating medical problems including cancer, addiction, cardiovascular disease, obesity, and infectious disease. For more information, please visit: Department of Pharmacology | Medical School - University of Minnesota (umn.edu) How To Apply Applications must be submitted online. To be considered for this position, please click the Apply button and follow the instructions. You will have the opportunity to complete an online application for the position and attach a cover letter and resume. Additional documents may be attached after application by accessing your "My Job Applications" page and uploading documents in the "My Cover Letters and Attachments" section. Example language: This position requires that you attach LIST ATTACHMENT TYPES SUCH AS: a sample of scholarly work, a diversity statement, and a list of references. This position will remain open until filled. To request an accommodation during the application process, please e-mail employ@umn.edu or call (612) 624-UOHR (8647). Diversity Employment Requirements Any offer of employment is contingent upon the successful completion of a background check. Our presumption is that prospective employees are eligible to work here. Criminal convictions do not automatically disqualify finalists from employment. About the U of M The University of Minnesota, Twin Cities (UMTC) The University of Minnesota, Twin Cities (UMTC), is among the largest public research universities in the country, offering undergraduate, graduate, and professional students a multitude of opportunities for study and research. Located at the heart of one of the nation's most vibrant, diverse m tropolitan communities, students on the campuses in Minneapolis and St. Paul benefit from extensive partnerships with world-renowned health centers, international corporations, government agencies, and arts, nonprofit, and public service organizations. The University of Minnesota offers a comprehensive benefits package including: Competitive wages, paid holidays, vacation and sick leave Low cost medical, dental, and pharmacy plans Health care and dependent daycare flexible spending accounts Excellent retirement plans with employer match Disability and employer paid life insurance Wellbeing program with reduced insurance premiums Tuition reimbursement opportunities covering 75%-100% of eligible tuition Student loan forgiveness opportunity Opportunities for growth and promotion Employee Assistance Program For more information regarding benefits: https://humanresources.umn.edu/sites/humanresources.umn.edu/files/2020tcd-fpa-75100-ben-0105-10cs_final.pdf The University recognizes and values the importance of diversity and inclusion in enriching the employment experience of its employees and in supporting the academic mission. The University is committed to attracting and retaining employees with varying identities and backgrounds. The University of Minnesota provides equal access to and opportunity in its programs, facilities, and employment without regard to race, color, creed, religion, national origin, gender, age, marital status, disability, public assistance status, veteran status, sexual orientation, gender identity, or gender expression. To learn more about diversity at the U: http://diversity.umn.edu.