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University of North Carolina- Chapel Hill Research Associate: Library Prep/QC Manager HTSF in NC-Chapel-Hill, United States

Employment Type: Permanent Staff (EHRA NF)

Vacancy ID: NF0008480

Salary Range: $65,000-$85,000

Position Summary/Description:

The primary purpose of this position is to manage the Library Preparation and QC team supporting the High Throughput Sequencing Facility ( HTSF ), part of the Integrated Genomics Core in the UNC School of Medicine. The HTSF mission is to apply the tools of high throughput sequencing technology and experience to enrich medicine and basic biological research at The University of North Carolina. High-throughput sequencing is an extremely fast developing technology that is used to extract genetic and genomic data from a broad spectrum of biological materials. This information is used to help identify the causes of complex diseases such as cancer, diabetes and cardiovascular disease and demonstrate the underlying bases for multiple types of infectious diseases. The Library Prep Manager ( LPM ) will manage the staff, laboratories, and instruments conducting library preparation and quality control in support of HTSF projects. This requires development and management of multiple and complex staffing and instrumentation long-range and day to day plans and schedules to accomplish research objectives. The PM is responsible for recruiting and hiring new staff, training new staff on a wide range of technologies, daily work assignments and supervision, professional development and mentoring of staff (currently 4 staff), conflict and grievance resolution; troubleshooting and root cause analysis when problems or quality issues are noted, and delivery of data to customers. The PM also interacts with prospective customers and principal investigators (PI’s), advises PI’s on appropriate research technical approaches, develops or directs the development of novel or new research approaches or techniques, and manages research projects as they are executed in the labs. The LPM coordinates the activities of multiple research laboratories with significant complexity. This includes managing the purchasing of supplies and reagents supporting multiple complex labs (over $3M/year); coordinating and managing capital equipment purchases; managing laboratory facility issues; and budgeting and managing annual operating expenses (over $4M/year). The LPM also manages larger research projects for both internal ( UNC ) projects and external contracts. This includes preparation of proposals and cost quotes/budgets; technical oversight and recommendations to the clients; oversight of technical work is it proceeds; frequent client updates and communications; schedule management; and managing costs/budgets for $2M in project revenue.

Education and Experience:

Laboratory experience in a next generation sequencing environment. Extensive experience in grant and proposal development and administration, including budgeting, expense monitoring, and progress reporting; strong communication skills with individuals at all levels within an organization; excellent writing skills demonstrated to yield grant awards, publications, and measurable coalition growth; and strength in organization. Demonstrated attention to detail; ability to collaborate and work independently; confidence in decision-making independently and with organizational leadership; supervision and oversight of dynamic teams; and ability to adapt quickly to a constantly growing and evolving coalition. Notable experience and knowledge of relevant intellectual content related to next generation sequencing library preparation techniques and technologies; experience evaluating new technologies and developing new methods/procedures; working knowledge of sequencing instrumentation and technologies; experience on troubleshooting and diagnosing issues with library preparation automation equipment and sequencers; and demonstrated interest and action toward continuing education of relevant topic areas.

Essential Skills:

Bachelor’s degree in a discipline related to the area of assignment, or equivalent combination of training and experience. All degrees must be received from appropriately accredited institutions. Experience in a microbiology laboratory environment. Working knowledge of next generation sequencing and library preparation technologies.

AA/EEO Statement:

The University of North Carolina at Chapel Hill is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or status as a protected veteran.

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