As a community, the University of Rochester is defined by a deep commitment to Meliora - Ever Better. Embedded in that ideal are the values we share: equity, leadership, integrity, openness, respect, and accountability. Together, we will set the highest standards for how we treat each other to ensure our community is welcoming to all and is a place where all can thrive.

Job Location (Full Address):

601 Elmwood Ave, Rochester, New York, United States of America, 14642

Opening:

Worker Subtype:

Regular

Time Type:

Full time

Scheduled Weekly Hours:

40

Department:

400166 Cancer Center M&D

Work Shift:

UR - Day (United States of America)

Range:

UR URG 106 H

Compensation Range:

$21.36 - $29.90

The referenced pay range represents the minimum and maximum compensation for this job. Individual annual salaries/hourly rates will be set within the job's compensation range, and will be determined by considering factors including, but not limited to, market data, education, experience, qualifications, expertise of the individual, and internal equity considerations.

Responsibilities:

To provide research support by independent or semi-supervised coordination and execution of experiments to establish the function and therapeutic targeting of various oncogenes of interest in myeloid leukemia to the principal investigators Dr. Jeevisha Bajaj in the James P. Wilmot Cancer Institute and the Department of Biomedical Genetics. The goals of this project are to identify novel regulators of disease progression and determine their mechanisms of action in an effort to develop novel therapies for myeloid diseases. This individual is expected to conduct in vitro and animal experiments and process/use human or animal tissue samples to design and conduct experiments that should support publication of manuscripts in scientific journals and grant proposals in timely manner. This position requires that the individual be able to conduct, troubleshoot and assist in redesigning experiments as needed.

TYPICAL ASSIGNMENTS AND RESPONSIBILITIES:

• Assist in the design of flow cytometry panels. Compensate and assist in analyzing flow cytometry data and perform flow cytometry analysis. Prepare cells by staining for flow cytometry analysis, multi-parameter flow cytometry and cell sorting, using scientific techniques such as cell sorting and immunohistochemistry.

• Animal experiments, breeding and maintenance of wild-type and gene specific knockout mice under development. Xenografting cancer cells in irradiated immune-competent of in immunodeficient mice, monitoring disease

• progression, analyzing tumors post sacrifice.

• Perform cell culture and manipulation of human cell lines including cloning for in vivo and in vitro experiments and assist with general lab assays including genotyping, gene expression analysis by RT-PCR and western blotting etc.

• Analyze and interpret data, participate in regular lab meetings including presentation of results. Develop figures and write methodologies for results to be published or included in the grant applications.

• Oversight responsibility of lab supplies, safety compliance, overseeing the utilization/maintenance of various instrumentations and lab equipment.

REQUIREMENTS:

• Associate's degree or degree in biological sciences with 4-5 years laboratory experience or equivalent combination of education and experience required.

• Expertise with animal experiments, breeding, colony maintenance, xenograft implantation in nude or NSG mice, multispectral imaging flow cytometry, microscopy and molecular biology techniques including cloning and PCR are essential required.

• Candidate must have excellent command of oral and written English language and work in a collaborative work environment. Candidate must be able to work with rodents and must complete human subjects research training required.

• Proficiency in Prism Graph Pad, MS Word, Excel, Photoshop, PowerPoint, FlowJo, and statistical software. Occasional weekend and evening hours may be necessary.

8 AM-4:30 PM

EOE Minorities / Females / Protected Veterans / Disabled:

The University of Rochester is committed to fostering, cultivating, and preserving a culture of equity, diversity, and inclusion to advance the University’s mission to Learn, Discover, Heal, Create – and Make the World Ever Better. In support of our values and those of our society, the University is committed to not discriminating on the basis of age, color, disability, ethnicity, gender identity or expression, genetic information, marital status, military/veteran status, national origin, race, religion/creed, sex, sexual orientation, citizenship status, or any other status protected by law. This commitment extends to the administration of our policies, admissions, employment, access, and recruitment of candidates from underrepresented populations, veterans, and persons with disabilities consistent with these values and government contractor Affirmative Action obligations.

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Learn. Discover. Heal. Create.

Located in western New York, Rochester is our namesake and our home. One of the world’s leading research universities, Rochester has a long tradition of breaking boundaries—always pushing and questioning, learning and unlearning. We transform ideas into enterprises that create value and make the world ever better.

If you’re looking for a career in higher education or health care, the University of Rochester may offer the perfect opportunity for your background and goals

At the University of Rochester, we commit to diversity, equity, and inclusion and united by a strong commitment to be ever better—Meliora. It is an ideal that informs our shared mission to ensure all members of our community feel safe, respected, included, and valued.