Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Medical Senior Director – Early Development, Oncology

What you will do

Let’s do this. Let’s change the world. In this vital role you will lead early phase clinical development of oncology compounds from first-in-human studies through proof of concept. They effectively define, design, and implement early phase clinical and translational projects as the initial strategy for drug development. They typically serve as clinical project leaders for one or more of Amgen’s Product Strategy Teams through their role as an Early Development Leader (EDL).

These experts represent Early Development internally and externally, contributing intellectual insight into experimental design and data analysis. They provide subject matter expertise in clinical and translational science as well as biology and the treatment of cancer.

Responsibilities:

• Leader of the Evidence Generation Team (EGT) and accountable for its deliverables, namely defining the early clinical development plan and overseeing its execution.

• Serve as an internal clinical expert in translational and clinical oncology and is capable of effective clinical representation on early preclinical assets communicating critical clinical needs, attributes and impact on molecule pre-development.

• Provide mentorship to junior medical directors and medical science directors in early clinical development.

• Evaluate external opportunities for partnering or licensing new oncology assets as a clinical representative to business development projects.

• Present information internally and externally, anticipating and proactively managing problems across a broad spectrum of cross-functional teams.

• Effectively liaise with Global Development Leads (GDL) to help develop global strategy for oncology assets transitioning to late stage.

• Identify and coordinate clinical approaches to operational issues and assign monitoring and safety reporting resources.

• Responsible for the medical monitoring plan of various oncology assets and in some cases accountable for oversight of multiple studies.

• Strong cross-functional collaborator with Research, Regulatory, Precision Medicine and other functions.

• Provide guidance and assistance in the identification and management of oncology phase 1 collaborators, consultants, and/or Clinical Research Organizations (CROs) in the completion of key projects.

• Ensure appropriate training, recruitment, and development requirements for matrix team resources.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a leader with these qualifications.

Basic Qualifications:

MD or DO degree from an accredited medical school

AND

5 years of clinical research and/or basic science research experience

And

5 years of managerial experience directly managing people and/or leadership experience leading teams, projects, programs or directing the allocation of resources

Preferred Qualifications:

• Strong basic science background in academia or industry

• Prior experience authoring, monitoring, analyzing, and presenting oncology clinical trials

• Effective presentation and communication abilities (both written and oral)

• Ability to anticipate problems and find creative solutions

• In-depth understanding of the scientific method and clinical applications based on medical, scientific, and practical rationale including working knowledge of biomarker methods and clinical imaging endpoints

• A record of high-quality peer-reviewed publications

• Experience functioning as a medical expert in a complex matrixed environment

• Previous experience in early phase development and/or biomarker work

• Demonstrated expertise in conducting translational and/or clinical oncology research

• Expertise in Spotfire or other data analysis tools

• Knowledge of GCP, EMA, and FDA policies

• Expertise in authoring clinical sections of CTA or INDs

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The annual base salary range for this opportunity in the U.S. (excluding Puerto Rico) is [salary range].

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts

• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

• Stock-based long-term incentives

• Award-winning time-off plans

• Flexible work models, including remote and hybrid work arrangements, where possible

Apply now

for a career that defies imagination

Objects in your future are closer than they appear. Join us.

careers.amgen.com

Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.